Arctium lappa L.: Chemical composition, antioxidants, phytochemical compounds and use for healing activity
Keywords:hydroethanolic extract, skin healing, Burdock
Arctium lappa L, popularly known as burdock, is a medicinal plant with wide application in chinese folk medicine. The objective of the present work was to proceed hydroethanolic extraction of the leaves, to analyze the chemical compounds as proteins, phenols, antioxidants, phytochemical and its skin healing potential in exposed cutaneous lesions in rats treated with gel containing the extract. For preparation the extract, fresh leaves of the burdock plant were obtained from Sitio Wadt located in Valinhos, SP and dried. 50g of dry leaves was subjected to percolation. Extract was tested to quantify proteins, phenols, and antioxidant capability. For skin healing of wound in rats, it was used male Wistar rats, divided in three groups (treated, control and fibrinase). Was performed daily application over the wound and healing evaluated macroscopically and measured by digital planimetry. Results demonstrated that hydroethanolic extract of leaves presented proteins, phenols, phenolic compounds and antioxidants. In animals, fibrinase was not as efficient as burdock extract and when compared to control group. It is possible to conclude that the gel with burdock extract is effective at skin healing in rats, being used as a phytoterapic, besides possessing antioxidant activity.